TAILORED ANTICOAGULANT TREATMENT AFTER A FIRST VENOUS THROMBOEMBOLISM: PROTOCOL OF THE LEIDEN THROMBOSIS RECURRENCE RISK PREVENTION (L-TRRIP) STUDY - COHORT-BASED RANDOMISED CONTROLLED TRIAL

Tailored anticoagulant treatment after a first venous thromboembolism: protocol of the Leiden Thrombosis Recurrence Risk Prevention (L-TRRiP) study - cohort-based randomised controlled trial

Introduction Patients with a first venous thromboembolism (VTE) are at risk of recurrence.Recurrent VTE (rVTE) can be prevented by extended anticoagulant therapy, but this comes at the cost of an increased risk of bleeding.It is still uncertain whether patients with an intermediate recurrence risk or with a high recurrence and high bleeding risk wi

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Zingiber zerumbet flower stem postharvest characterization

About the Zingiber zerumbet little is known about its cut flower postharvest and market, despite its high ornamental potential.The inflorescences, which resemble a compact cone, emerge from the base of the plants and start with green color changing to red with the age.This study objective was to characterize floral stem of ornamental ginger in two

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Detection and Location of Surface Damage Using Third-Order Combined Harmonic Waves Generated by Non-Collinear Ultrasonic Waves Mixing

Metals which are widely used in many types of industries are usually subjected to fatigue and surface corrosion.There is a demand to detect the surface damage caused by fatigue and corrosion at an early stage to ensure the structural integrity.In this paper, a novel nonlinear ultrasonic technique based on the measure of third-order combined harmoni

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Stem cell-derived cardiomyocytes expressing a dominant negative pacemaker HCN4 channel do not reduce the risk of graft-related arrhythmias

BackgroundHuman pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) show tremendous promise for cardiac regeneration following myocardial infarction (MI), but their transplantation gives rise to transient ventricular tachycardia (VT) in large-animal MI models, representing a major hurdle to translation.Our group previously graco ascent reported

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